Amy was twelve years younger than Andrea and that caused no small amount of tension between the sisters. She was resentful of Andrea leaving her behind at home and not coming back often enough to visit and be a part of her life. The experience of the apocalypse strengthened their bond enormously, though Amy was still often frustrated by Andrea correcting her, judging her, and generally telling her what to do. However, Amy worshipped her older sister, wanting to be just like her.
Still young, Amy was impetuous and eternally optimistic. She helped look out for the kids in the camp, was quick to defend others' actions when she saw them as being protective and generally tried to keep the peace among her fellow survivors.
In the fourth episode "Vatos", the group's camp is attacked by zombies that wandered up into the hills from Atlanta. Amy is taken by surprise as she steps out of Dale's camper van and is bitten on the arm and on the neck. The blood loss from her neck wound soon kills her and Andrea spends the night weeping over her sister's body. In the morning, Amy reanimates as a zombie while Andrea still cradles her in her arms. Andrea then says her goodbyes before shooting Amy in the head with a revolver.